Yukihime brings Tōta and Kurōmaru to UQ Holder HQ where they meet a whole team of immortals like them. As new recruits, they are shown a cold shoulder. To earn respect and become fullfledged members of UQ Holder, they must pass an initiation test. Without any warning, Tōta and Kurōmaru are dropped into a murky underground maze. Their mission: to escape from this dark monsterinfested labyrinth within eight years. Tōta says he'll get out in a week....

Tota meets Kirië Sakurame, a mysterious member of UQ Holder. Kirië looks like a little girl, but is apparently the wealthy patron of UQ Holder. Tota accompanies her on a trip to the tower to meet Karin (returning from the Moon), but the trip appears to have another purpose. The powerful wizard Fate Averruncus, former ally of Tota's grandfather Negi, wants to take possession of Tota for reasons unknown. Despite having Karin, Ikku, Kirië and Kuromaru...

After Kitty's shocking revelation, Tōta goes to met with her again, but all he finds is a note telling him to come back in four days, or to her, 287 years. In the meantime, Dana gives Tōta some big news: she's prepared a finishing move for him! But there's a catch: the book on how to perform the move is hidden in a box in the monster-infested castle ruins below...a challenge even before Dana sends him to a distant starting point. Can Tōta complete...

After Tōta's shocking proposal to Kitty, the rest of the UQ Holder gang realizes they may never get a chance to act on their own feelings. New rivals Shinobu and Mizore appear on the scene, and join the competition for Tōta's affection. Meanwhile, Kuromaru and Kirië are having trouble controlling their own emotions. Tōta's only concern is saving the world and protecting Kitty-but what plans do the other members of the group have for him?

After their showdown, Negi asks Tōta to follow in his footsteps. The request brings Tōta and Kirië to Kyoto in search of an old workshop owned by Nagi Springfield, Negi's father and Tōta's great-grandfather. But uncovering the workshop isn't such an easy task, and with Kirië struggling over her conflicted feelings for Tōta, the trip might be more than the two of them can handle.

With Tokyo making way for the upcoming Mahora Martial Arts Tournament and Neo Olympics, Tōta and company couldn't be more fired up. But before the games can begin, Mizore, Shinobu, and Kirië face off in the God Bull Speeder Bike Race-with Tōta's love as the prize! And when Kirië and Tōta accidentally freeze time at the finish line, they find themselves face-to-face with Cutlass...and a few more not-so-friendly faces, including Tōta's grandfather!...

Tota, Kuromaru and Karin are on a mission protecting the poor residents of the slums when they come under fierce attack by powerful enemies who seem to specialize in hunting down and killing immortals. Tota and Kuromaru take a nasty beat down and in a moment of desperation, Tota finds a new power that may be great or terrible or both! From the creator of Love Hina and Negima!

To get the drop on UQ Holder's true enemy, Fate Averruncus, Tota and the others head for Ama no Mihashira. At first, UQ Holder feels helpless before Fate's overwhelming strength, but then, with some help from Kirië's abilities, they manage to seize him! At last, for the first time in 20 years, Fate and Evangeline meet again. The moment their eyes lock in confrontation, the two hurl themselves into battle!

Negi Springfield, the boy wizard of the hit manga Negima!, fought and won many battles. Now it is decades later and Negi's grandson(!), a little boy name Touta, dreams of leaving his quiet village and heading to the City. But first he must defeat his teacher... the immortal vampire, Evangeline!